Study: Cannabinoids May Treat Persistent Inflammatory Pain

by Anthony Martinelli

Activation of the CB2 (cannabinoid type 2) receptor – something done naturally through the consumption of cannabinoids – may treat persistent inflammatory pain.

This is according to new research published in the Journal of Neuroscience, and published online by the U.S. National Institute of Health.

For the study, researchers at the Oregon Health & Science University examined how a cannabinoid receptor agonist (meant to mimic the effects of natural cannabinoids) effected “persistent inflammation induced by complete Freund’s adjuvant (CFA)”.

According to researchers; “Our data provide evidence that CB2 receptor function emerges in the RVM [rostral ventromedial medulla; a relay in the descending pain modulatory system and an important site of endocannabinoid modulation of pain] in persistent inflammation and that selective CB2 receptor agonists may be useful for treatment of persistent inflammatory pain.”

According to the study’s significant statement:

“These studies demonstrate that endocannabinoid signaling to CB1 and CB2 receptors in adult rostral ventromedial medulla is altered in persistent inflammation. The emergence of CB2 receptor function in the rostral ventromedial medulla provides additional rationale for the development of CB2 receptor-selective agonists as useful therapeutics for chronic inflammatory pain.

The full text and abstract of this study can be found by clicking here.

This study joins a list of dozens that have shown that cannabinoids can treat and prevent inflammation, including one released just last month in the FASEB Journal which found that cannabis may treat chronic inflammation.

Source:  The Joint Blog

Shark Tank’s Kevin O’Leary to Run for Prime Minister of Canada, Supports Marijuana Legalization

Billionaire investor Kevin O’Leary has spent years gaining notoriety as a mainstay member of ABC’s Shark Tank. Prior to that he spent eight years on the Canadian version of the show, Dragon’s Den. Now O’Leary wants to be the Prime Minister of Canada.


In an announcement that might draw deja vu to Donald Trump’s announcement (both are billionaire reality stars running on a conservative platform), O’Leary says he is running for leadership of Canada’s Conservative Party in an effort to take over the role of Prime Minister from Justin Trudeau. Trudeau is up for reelection in 2019.

“I am the only one that can defeat Trudeau,” O’Leary, 62, stated on Facebook. O’Leary believes that Trudeau is placing a huge amount of debt upon the country, which he says he has ideas to fix (ideas he has yet to release).

Breaking with the Conservative Party, O’Leary is actually a supporter of legalizing marijuana, something that Trudeau campaigned on (but has yet to follow through with).

In a recent interview with Business Insider, O’Leary stated; “This is like the end of prohibition. It’s going to be a remarkable opportunity. The cashflow in Colorado is three times what they thought it was going to be. They did the right thing by legalizing it and it’s now a huge cash crop. People should not be going to jail for marijuana. This is substance that’s been used by humans for thousands of years. It’s stupid what we’ve done to it, and I think it has to be federally legal.”

Also in breaking with the Conservative Party, O’Leary says he’s a supporter of LGBT rights and assisted suicide, among other progressive causes.

Source: The Joint Blog